Why do cat scratches itch?

Why do cat scratches itch? - briefly

Cat scratches often cause itching due to the release of histamines in response to the injury. This is a normal part of the body's immune reaction to trauma or foreign substances.

Why do cat scratches itch? - in detail

Cat scratches often cause intense itching due to a combination of factors related to the immune system's response and the nature of feline saliva. When a cat scratches, its claws can introduce bacteria into the wound, leading to an infection. The body's immune system responds to this infection by releasing histamines, which are chemicals that help to fight off pathogens. Histamines cause blood vessels to dilate and become more permeable, allowing white blood cells and other protective substances to reach the affected area more easily. This process also stimulates nerve endings, resulting in the sensation of itching. Additionally, cat saliva contains a protein called Fel d 1, which is responsible for most allergic reactions to cats. When this protein enters the skin through a scratch, it can trigger an allergic response in some individuals, further exacerbating the itch. The itching sensation serves as a signal to the body that something is wrong and prompts the individual to take action to address the issue.