Why can't folded-eared cats be bred with folded-eared cats?

Why can't folded-eared cats be bred with folded-eared cats? - briefly

Folded-eared cats cannot be bred together due to potential genetic issues. This is because the gene responsible for their unique ear shape is dominant and can lead to offspring with severe health problems if both parents carry it.

Why can't folded-eared cats be bred with folded-eared cats? - in detail

The inability to breed folded-eared cats, such as Scottish Folds, exclusively among themselves is primarily due to genetic constraints and ethical considerations.

Genetically, the distinctive ear fold in these cats is caused by a dominant gene mutation that affects cartilage development. This mutation leads to an abnormal protein structure called collagen II, which results in the characteristic folded ears. However, this same mutation can also cause serious health issues, such as osteochondrodysplasia, a form of bone and cartilage malformation that leads to painful joints and mobility problems.

Breeding two Scottish Folds together increases the likelihood that both parents will pass on the mutated gene to their offspring. If this occurs, the resulting kittens may inherit two copies of the mutated gene, which can exacerbate the health issues associated with osteochondrodysplasia. Ethical breeding practices aim to minimize these risks by avoiding matings that could result in double doses of harmful genes.

To mitigate these genetic risks, responsible breeders often cross Scottish Folds with other cat breeds, such as American Shorthairs or British Shorthairs, which do not carry the ear fold mutation but share similar physical traits. This practice, known as outcrossing, helps to dilute the harmful effects of the mutated gene while preserving the desirable folded-ear trait in future generations.

In conclusion, breeding folded-eared cats with each other is discouraged due to the potential for exacerbating genetic health issues. Responsible breeding practices emphasize the importance of outcrossing to maintain the overall well-being and longevity of these unique felines.