What is GGT in cats? - briefly
GGT, or gamma-glutamyl transferase, is an enzyme in cats that helps assess liver and bile duct health, often measured through blood tests. Elevated GGT levels can indicate liver disease or bile flow obstruction.
What is GGT in cats? - in detail
Gamma-glutamyl transferase (GGT) is an enzyme found in various tissues, with significant concentrations in the liver, kidneys, and pancreas. In cats, GGT is primarily associated with liver function and is often measured as part of diagnostic blood tests to assess hepatic health. Elevated levels of GGT in cats can indicate liver damage, bile duct obstruction, or other hepatobiliary disorders. This enzyme is particularly useful in diagnosing cholestatic conditions, as it is more sensitive to bile flow disturbances than other liver enzymes. GGT is membrane-bound and is involved in the metabolism of glutathione, a critical antioxidant, and the transport of amino acids across cell membranes. While GGT elevation is not specific to any single disease, it serves as a valuable marker for veterinarians to identify and monitor liver-related issues. Conditions such as hepatic lipidosis, cholangiohepatitis, or neoplasia may cause increased GGT activity. However, interpretation of GGT levels should always be done in conjunction with other diagnostic findings, including clinical signs, imaging, and additional liver enzyme measurements, to ensure an accurate diagnosis and appropriate treatment plan for the feline patient.