Can Nexgard be given to cats? - briefly
No, Nexgard should not be given to cats. It is specifically formulated for dogs and can cause serious health issues in cats, including seizures and death.
Can Nexgard be given to cats? - in detail
Nexgard is a popular medication used to prevent and treat flea infestations in dogs, but its use in cats is not recommended. Here's a detailed explanation of why this is the case:
Nexgard contains the active ingredient afoxolaner, which belongs to the isoxazoline class of compounds. This class of drugs has been shown to be highly effective against fleas and ticks in dogs. However, the safety profile of isoxazolines in cats differs significantly from that in dogs.
In cats, isoxazolines can cause serious adverse effects, including neurological symptoms such as tremors, seizures, and even death. The exact mechanism behind these reactions is not fully understood, but it is believed to be related to the metabolism of isoxazolines in felines. Cats have a different liver enzyme system compared to dogs, which can lead to slower metabolism and increased toxicity of the drug.
Several studies have highlighted the risks associated with using isoxazolines in cats. In one study, cats treated with an isoxazoline product experienced severe neurological symptoms within hours of administration. Another study found that even at lower doses, isoxazolines could cause adverse reactions in cats.
Given these serious risks, veterinary guidelines strongly advise against using Nexgard or any other isoxazoline products in cats. Instead, there are cat-specific flea and tick preventatives available that have been thoroughly tested and proven safe for felines. These alternatives include topical treatments like Frontline and Revolution, as well as oral medications such as Bravecto for cats.
In conclusion, while Nexgard is a highly effective medication for dogs, it should not be given to cats due to the potential for severe adverse reactions. It is essential to consult with a veterinarian to ensure that your cat receives appropriate and safe flea and tick prevention treatment.