Can cats have Ivermectin? - briefly
Cats should not be given Ivermectin as it can be toxic to them. The drug is primarily intended for use in dogs and other animals, but it can cause serious health issues in cats.
Can cats have Ivermectin? - in detail
Cats and Ivermectin: A Detailed Examination
Ivermectin is a widely used anti-parasitic medication, effective against a variety of internal and external parasites in both humans and animals. However, its use in cats requires careful consideration due to the species' unique physiological characteristics and sensitivities.
Cats possess a genetic mutation that affects their ability to metabolize certain drugs, including Ivermectin. This mutation is particularly common in breeds such as Scottish Fold, American Shorthair, and Domestic Shorthair. The mutated gene, MDR1 (P-glycoprotein), plays a crucial role in the blood-brain barrier, preventing harmful substances from entering the brain. In cats with this mutation, Ivermectin can accumulate in the brain, leading to potentially fatal neurological symptoms such as ataxia, tremors, seizures, and even coma or death.
The risk of adverse reactions is not solely dependent on the cat's breed but also on the dose administered. Even small amounts of Ivermectin can be dangerous for cats with the MDR1 mutation. It is crucial to note that not all cats carry this genetic mutation, and some may tolerate Ivermectin better than others. However, due to the high prevalence of the mutation and the severe consequences of an overdose, veterinarians often advise against using Ivermectin in cats unless absolutely necessary and under strict supervision.
In cases where treatment with Ivermectin is deemed essential, such as for advanced ear mite infestations resistant to other treatments, a vet may prescribe it. However, they will likely perform genetic testing first to determine if the cat carries the MDR1 mutation. If the test confirms the presence of the mutation, alternative treatments are typically recommended.
It is also important to be cautious with topical Ivermectin products designed for dogs, as cats can ingest these substances during grooming or through direct contact. Even small amounts absorbed through the skin can lead to toxicity in susceptible cats.
In summary, while Ivermectin can be a potent anti-parasitic medication for many animals, its use in cats is fraught with risks due to their unique genetic predisposition. Owners and veterinary professionals should exercise extreme caution when considering this drug for feline patients. Genetic testing, careful dosage calculation, and close monitoring are essential steps to ensure the safety of cats treated with Ivermectin.